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KMID : 0613819990090060677
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Journal of Life Science
1999 Volume.9 No. 6 p.677 ~ p.683
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Antitumor Activity of Gamdutang Aqua-Acupuncture Solution
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Abstract
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Gamdutang aqua-acupuncture solution (GAS), Gamdutang water-extracted solution (GWS) and Dae-Gamdutang aqua-acupuncture solution (DGAS) were prepared and tested for antitumor activities. It was shown to possess considerable toxicity toward various tumor cell lines. Concentration of 5 × and 10× of GAS resulted in more than 70% inhibition of growth in Ehrlich ascites tumor cells (EATC), Hepa1c1c7 and A549. GAS at concentrations of 5× and 10× revealed more than 60% inhibition in HeLa. GWS showed more than 50% inhibition of growth with EATC and HeLa at concentrations of 5× and 10×, respectively. Toxicity assay with GWS in Hepa1c1c7 and A549 revealed that more than 80% inhibition of growth at the concentration of 5× and 10×. In morphological study, the number of cells were decreased, and the shape of cells was round-form in EATC, Hepa1c1c7 ; Morphological study
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